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OraRez® W

Trade name: OraRez® W

Chemical description: Free acid of the copolymer of methyl vinyl ether-co-maleic anhydride

CAS No. : 25153-40-6

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Product Details

Properties:

Soluble in water and alcohols; Excellent wet adhesive strength; Bioadhesive; Strong chelating/complexing properties; Solution and film properties adjustable via carboxylic acid neutralization/reaction.

Specifications：

OraRez®W	20P	100P
Appearance	White to off-white powder
PH (5% in aq. soln.)	1.5-2.5	1.5-2.5
Moisture%max	6.0	6.0
Specific viscosity SV (1% aq. soln.)	0.4-1.5	4.0-10.0
Heavy metals ppm max.	10	10

Applications:

1 Oral preparations: denture adhesives, ulcer patches and periodontal gels, delivering prolonged mucoadhesion to enhance local therapeutic efficacy in the oral cavity.

2 Oral films: film-forming agent for orodispersible films and orally disintegrating tablets, with an additional function of stabilizing active pharmaceutical ingredients.

3 Mucosal gels: sustained-release formulations for nasal and vaginal administration that reduce liquid runoff and extend the duration of therapeutic action.

4 Transdermal preparations: base material for microneedles and topical analgesic patches to facilitate skin permeation of drugs.

5 Nano drug delivery: coating carrier for poorly soluble drugs and herbal extracts to improve dissolution rate and colloidal stability.

6 Medical dressings: matrix for antibacterial wound hydrogels that moisturize tissues, accelerate healing and avoid adhesion to wounds.

7 General pharmaceutical excipients: thickener for gels and suspensions, chelating stabilizer for metal ions, extending the shelf life of finished formulations.

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